Supporting Your Health on GLP-1 Medications! 
Are you using GLP-1 medications for weight loss or blood sugar management? While these medications can be effective, they may also lead to muscle loss, frozen stomach, pancreatitis, and other challenges.
As a functional health practitioner, I follow science-backed protocols developed by leading researchers in the nutrition industry to help support your body during your journey. With the right supplements, you can maintain
muscle, improve digestion, and protect vital organs while optimizing your results.
GLP-1 (Glucagon-Like Peptide-1) receptor agonists, such as semaglutide (Ozempic, Wegovy) and liraglutide (Saxenda, Victoza), are widely used for weight loss and blood sugar management in type 2 diabetes. While these medications can be highly effective, they also come with a range of potential side effects. Understanding these effects can help individuals better manage their health and mitigate risks.
1. Muscle Loss (Lean Mass Reduction)
Many individuals on GLP-1 medications experience muscle loss along with fat loss. This happens because:
Rapid weight loss can lead to a decrease in both fat and lean muscle mass.
Reduced appetite from GLP-1 agonists can lead to insufficient protein intake, which contributes to muscle breakdown.
If strength training and proper supplementation aren’t prioritized, the body may not maintain optimal muscle function.
Prevention:
Prioritize protein intake (aim for 1.2–2.0g per kg of body weight).
Engage in strength training exercises at least 2–3 times per week.
Use muscle-supporting supplements like collagen, BCAAs, creatine, and omega-3 fatty acids.
2. "Frozen Stomach" (Gastroparesis-like Symptoms)
GLP-1 medications slow down gastric emptying, meaning food stays in the stomach longer. While this helps with appetite control, in some cases, it leads to severe delayed gastric emptying, also known as "frozen stomach."
Symptoms:
Feeling overly full after small meals
Bloating and nausea
Vomiting undigested food
Severe constipation
Prevention & Management:
Eat smaller, more frequent meals to avoid overwhelming the stomach.
Chew food thoroughly and focus on easily digestible options.
Stay hydrated, as dehydration can worsen digestion issues.
Use digestive enzymes and prokinetic supplements to support stomach motility.
3. Pancreatitis (Inflammation of the Pancreas)
GLP-1 medications have been associated with an increased risk of pancreatitis, though it’s rare. The mechanism isn’t fully understood, but the medication’s effect on insulin and digestive enzyme regulation may contribute.
Warning Signs of Pancreatitis:
Severe, persistent abdominal pain (especially radiating to the back)
Nausea and vomiting
Fever and rapid heartbeat
Prevention & Management:
Avoid alcohol and high-fat meals, which stress the pancreas.
Incorporate anti-inflammatory foods and supplements like turmeric and omega-3s.
Seek immediate medical attention if you experience severe pain.
4. Nausea, Vomiting, and Gastrointestinal Issues
Since GLP-1 medications impact digestion, many people struggle with nausea and vomiting, especially when starting the medication or increasing the dose.
Prevention & Management:
Start with lower doses and gradually increase as tolerated.
Ginger supplements or teas can help reduce nausea.
Avoid greasy, spicy, or high-fat foods, which can worsen symptoms.
Electrolyte replenishment (magnesium, potassium, sodium) can help maintain hydration.
5. Gallbladder Issues (Gallstones and Inflammation)
Rapid weight loss from GLP-1 medications increases the risk of gallstones, which can lead to gallbladder inflammation.
Signs of Gallbladder Issues:
Sharp pain in the upper right abdomen (especially after fatty meals)
Nausea and bloating
Jaundice (yellowing of skin or eyes) in severe cases
Prevention:
Maintain a balanced fat intake—don't eliminate fat entirely, as moderate consumption keeps the gallbladder functioning.
Consider bile-supporting supplements (e.g., taurine, ox bile, digestive enzymes).
Stay hydrated and avoid rapid, extreme weight loss.
6. Nutrient Deficiencies
Since GLP-1 medications reduce food intake, nutrient deficiencies can develop over time, particularly in:
Protein and essential amino acids (due to reduced appetite)
Electrolytes (magnesium, potassium, sodium) (due to nausea, vomiting, and hydration issues)
Vitamin B12 and iron (common in long-term users)
Prevention & Management:
Supplement with high-quality vitamins and minerals tailored for GLP-1 users.
Consume nutrient-dense foods even in small portions.
Regular blood tests to monitor vitamin and mineral levels.
7. Mood Changes and Mental Health Concerns
Some individuals on GLP-1 medications report mood swings, depression, or anxiety. While this isn’t fully understood, possible reasons include:
Nutrient deficiencies affecting brain function.
Hormonal changes due to weight loss and appetite suppression.
Psychological adjustments to rapid weight changes.
Prevention & Management:
Prioritize omega-3s, magnesium, and B vitamins for brain health.
Stay socially connected and seek support during weight loss transitions.
Monitor mood changes and consult a healthcare professional if needed.
Supporting Your Body on GLP-1 Medications
GLP-1 medications can be powerful tools for weight loss and metabolic health, but side effects can be minimized with the right approach.
Protein & muscle support to prevent muscle loss
Digestive support to avoid gastroparesis
Pancreas and gallbladder health monitoring
Electrolyte balance & nutrient optimization
Mental health awareness and self-care
By following science-backed protocols, you can stay strong, healthy, and vibrant while on GLP-1 medications!
Want to make sure you’re getting the right support? I offer targeted supplements based on leading scientific research to help you protect your body while using GLP-1 medications.
email/text me or comment below to learn more about the best supplements for you! Let's optimize your health together.
When your in a low place with your health you just need someone to believe in you. I Believe in YOU - Nurse Tanya
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